Identification of Non-HLA Genes Associated with Celiac Disease and Country-Specific Differences in a Large, International Pediatric Cohort

OBJECTIVES: There are significant geographical differences in the prevalence and incidence of celiac disease that cannot be explained by HLA alone. More than 40 loci outside of the HLA region have been associated with celiac disease. We investigated the roles of these non-HLA genes in the developmen...

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Published in:PLoS One
Main Authors: Sharma, Ashok, Liu, Xiang, Hadley, David, Hagopian, William, Liu, Edwin, Chen, Wei-Min, Onengut-Gumuscu, Suna, Simell, Ville, Rewers, Marian, Ziegler, Anette-G., Lernmark, Åke, Simell, Olli, Toppari, Jorma, Krischer, Jeffrey P., Akolkar, Beena, Rich, Stephen S., Agardh, Daniel, She, Jin-Xiong
Format: Artigo
Language:Inglês
Published: Public Library of Science 2016
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Research Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4807782/
https://ncbi.nlm.nih.gov/pubmed/27015091
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0152476
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