Risk of Pediatric Celiac Disease According to HLA Haplotype and Country

BACKGROUND: The presence of HLA haplotype DR3–DQ2 or DR4–DQ8 is associated with an increased risk of celiac disease. In addition, nearly all children with celiac disease have serum antibodies against tissue transglutaminase (tTG). METHODS: We studied 6403 children with HLA haplotype DR3–DQ2 or DR4–D...

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Autori principali: Liu, Edwin, Lee, Hye-Seung, Aronsson, Carin A., Hagopian, William A., Koletzko, Sibylle, Rewers, Marian J., Eisenbarth, George S., Bingley, Polly J., Bonifacio, Ezio, Simell, Ville, Agardh, Daniel
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2014
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4163840/
https://ncbi.nlm.nih.gov/pubmed/24988556
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1056/NEJMoa1313977
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