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Dynamic Alu Methylation during Normal Development, Aging, and Tumorigenesis

DNA methylation primarily occurs on CpG dinucleotides and plays an important role in transcriptional regulations during tissue development and cell differentiation. Over 25% of CpG dinucleotides in the human genome reside within Alu elements, the most abundant human repeats. The methylation of Alu e...

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Bibliografiske detaljer
Main Authors: Luo, Yanting, Lu, Xuemei, Xie, Hehuang
Format: Artigo
Sprog:Inglês
Udgivet: Hindawi Publishing Corporation 2014
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4163490/
https://ncbi.nlm.nih.gov/pubmed/25243180
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2014/784706
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