The Dynamic Epigenetic Landscape of the Retina During Development, Reprogramming, and Tumorigenesis

In the developing retina, multipotent neural progenitors undergo unidirectional differentiation in a precise spatiotemporal order. Here we profile the epigenetic and transcriptional changes that occur during retinogenesis in mice and humans. Although some progenitor genes and cell cycle genes were e...

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Udgivet i:Neuron
Main Authors: Aldiri, Issam, Xu, Beisi, Wang, Lu, Chen, Xiang, Hiler, Daniel, Griffiths, Lyra, Valentine, Marc, Shirinifard, Abbas, Thiagarajan, Suresh, Sablauer, Andras, Barabas, Marie-Elizabeth, Zhang, Jiakun, Johnson, Dianna, Frase, Sharon, Zhou, Xin, Easton, John, Zhang, Jinghui, Mardis, Elaine R., Wilson, Richard K., Downing, James R., Dyer, Michael A.
Format: Artigo
Sprog:Inglês
Udgivet: 2017
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5508517/
https://ncbi.nlm.nih.gov/pubmed/28472656
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.neuron.2017.04.022
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