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Reprogramming retinal neurons and standardized quantification of their differentiation in 3-dimensional retinal cultures

Postmitotic differentiated neurons are among the most difficult cells to reprogram into induced pluripotent stem cells (iPSCs) because they have poor viability when cultured as dissociated cells. Other protocols to reprogram postmitotic neurons have required the inactivation of the p53 tumor suppres...

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Detalhes bibliográficos
Publicado no:Nat Protoc
Main Authors: Hiler, Daniel J., Barabas, Marie E., Griffiths, Lyra M., Dyer, Michael A.
Formato: Artigo
Idioma:Inglês
Publicado em: 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5530375/
https://ncbi.nlm.nih.gov/pubmed/27658012
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nprot.2016.109
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