The dynamics of DNA methylation fidelity during mouse embryonic stem cell self-renewal and differentiation

The faithful transmission of DNA methylation patterns through cell divisions is essential for the daughter cells to retain a proper cell identity. To achieve a comprehensive assessment of methylation fidelity, we implemented a genome-scale hairpin bisulfite sequencing approach to generate methylatio...

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Bibliographische Detailangaben
Hauptverfasser: Zhao, Lei, Sun, Ming-an, Li, Zejuan, Bai, Xue, Yu, Miao, Wang, Min, Liang, Liji, Shao, Xiaojian, Arnovitz, Stephen, Wang, Qianfei, He, Chuan, Lu, Xuemei, Chen, Jianjun, Xie, Hehuang
Format: Artigo
Sprache:Inglês
Veröffentlicht: Cold Spring Harbor Laboratory Press 2014
Schlagworte:
Research
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4120083/
https://ncbi.nlm.nih.gov/pubmed/24835587
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gr.163147.113
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