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Deciphering the heterogeneity in DNA methylation patterns during stem cell differentiation and reprogramming

BACKGROUND: Human induced pluripotent stem cells (iPSCs) have a wide range of applications throughout the fields of basic research, disease modeling and drug screening. Epigenetic instable iPSCs with aberrant DNA methylation may divide and differentiate into cancer cells. Unfortunately, little effor...

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Detalhes bibliográficos
Publicado no:BMC Genomics
Main Authors: Shao, Xiaojian, Zhang, Cuiyun, Sun, Ming-An, Lu, Xuemei, Xie, Hehuang
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4242552/
https://ncbi.nlm.nih.gov/pubmed/25404570
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2164-15-978
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