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Deciphering the heterogeneity in DNA methylation patterns during stem cell differentiation and reprogramming

BACKGROUND: Human induced pluripotent stem cells (iPSCs) have a wide range of applications throughout the fields of basic research, disease modeling and drug screening. Epigenetic instable iPSCs with aberrant DNA methylation may divide and differentiate into cancer cells. Unfortunately, little effor...

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Bibliografske podrobnosti
izdano v:BMC Genomics
Main Authors: Shao, Xiaojian, Zhang, Cuiyun, Sun, Ming-An, Lu, Xuemei, Xie, Hehuang
Format: Artigo
Jezik:Inglês
Izdano: BioMed Central 2014
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC4242552/
https://ncbi.nlm.nih.gov/pubmed/25404570
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2164-15-978
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