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The Mcm2-7 Replicative Helicase: A Promising Chemotherapeutic Target

Numerous eukaryotic replication factors have served as chemotherapeutic targets. One replication factor that has largely escaped drug development is the Mcm2-7 replicative helicase. This heterohexameric complex forms the licensing system that assembles the replication machinery at origins during ini...

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Bibliografiske detaljer
Main Authors: Simon, Nicholas E., Schwacha, Anthony
Format: Artigo
Sprog:Inglês
Udgivet: Hindawi Publishing Corporation 2014
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4163376/
https://ncbi.nlm.nih.gov/pubmed/25243149
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2014/549719
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