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The Mcm2-7 Replicative Helicase: A Promising Chemotherapeutic Target
Numerous eukaryotic replication factors have served as chemotherapeutic targets. One replication factor that has largely escaped drug development is the Mcm2-7 replicative helicase. This heterohexameric complex forms the licensing system that assembles the replication machinery at origins during ini...
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| Hoofdauteurs: | , |
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| Formaat: | Artigo |
| Taal: | Inglês |
| Gepubliceerd in: |
Hindawi Publishing Corporation
2014
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| Onderwerpen: | |
| Online toegang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4163376/ https://ncbi.nlm.nih.gov/pubmed/25243149 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2014/549719 |
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