Quantitative Mass Spectrometry-Based Analysis of β-D-Glucosyl-5-hydroxymethyluracil in Genomic DNA of Trypanosoma brucei

β-D-glucosyl-5-hydroxymethyluracil (base J) is a hyper-modified nucleobase found in the nuclear DNA of kinetoplastid parasites. With replacement of a fraction of thymine in DNA, J is localized primarily in telomeric regions of all organisms carrying this modified base. The biosynthesis of J occurs i...

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Hlavní autoři: Liu, Shuo, Ji, Debin, Cliffe, Laura, Bullard, Whitney, Sabatini, Robert, Wang, Yinsheng
Médium: Artigo
Jazyk:Inglês
Vydáno: 2014
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Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4163122/
https://ncbi.nlm.nih.gov/pubmed/25078157
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s13361-014-0960-6
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