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Rational Design and Characterization of the Novel, Broad and Potent Bispecific HIV-1 Neutralizing Antibody iMabm36

While broadly neutralizing monoclonal antibodies (bNAbs) have always been considered potential therapeutic options for the prophylactic and treatment of HIV infection, their lack of breadth against all HIV variants has been one of the limiting factors. To provide sufficient neutralization breadth an...

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Detalhes bibliográficos
Main Authors: Sun, Ming, Pace, Craig S., Yao, Xin, Yu, Faye, Padte, Neal N., Huang, Yaoxing, Seaman, Michael S., Li, Qihan, Ho, David D.
Formato: Artigo
Idioma:Inglês
Publicado em: 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4163016/
https://ncbi.nlm.nih.gov/pubmed/24853313
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/QAI.0000000000000218
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