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p53 dynamics control cell fate

Cells transmit information through molecular signals that often show complex dynamical patterns. The dynamic behavior of the tumor suppressor p53 varies depending on the stimulus; in response to double-strand DNA breaks it shows a series of repeated pulses. Using a computational model, we identified...

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Autori principali: Purvis, Jeremy E., Karhohs, Kyle W., Mock, Caroline, Batchelor, Eric, Loewer, Alexander, Lahav, Galit
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2012
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4162876/
https://ncbi.nlm.nih.gov/pubmed/22700930
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/science.1218351
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