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Basal dynamics of p53 reveals transcriptionally attenuated pulses in cycling cells
The tumor suppressor p53 is activated by stress and leads to cellular outcomes such as apoptosis and cell cycle arrest. Its activation must be highly sensitive to ensure that cells react appropriately to damage. However, proliferating cells often encounter transient damage during normal growth, wher...
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| Главные авторы: | , , , |
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| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
2010
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3003696/ https://ncbi.nlm.nih.gov/pubmed/20598361 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cell.2010.05.031 |
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