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LONGITUDINALLY EXTENSIVE NMO SPINAL CORD PATHOLOGY PRODUCED BY PASSIVE TRANSFER OF NMO-IgG IN MICE LACKING COMPLEMENT INHIBITOR CD59
Spinal cord pathology with inflammatory, demyelinating lesions spanning three or more vertebral segments is a characteristic feature of neuromyelitis optica (NMO). NMO pathogenesis is thought to involve binding of immunoglobulin G anti-aquaporin-4 autoantibodies (NMO-IgG) to astrocytes, causing comp...
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| Main Authors: | , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2014
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4162764/ https://ncbi.nlm.nih.gov/pubmed/24698947 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jaut.2014.02.011 |
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