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Unique Neuromyelitis Optica Pathology Produced in Naïve Rats by Intracerebral Administration of NMO-IgG
Animal models of neuromyelitis optica (NMO) are needed for elucidation of disease mechanisms and for testing new therapeutics. Prior animal models of NMO involved administration of human anti-aquaporin-4 immunoglobulin G antibody (NMO-IgG) to rats with pre-existing neuroinflammation, or to naïve mic...
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| Main Authors: | , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2013
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3954950/ https://ncbi.nlm.nih.gov/pubmed/24190619 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00401-013-1204-8 |
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