Passively transferred human NMO-IgG exacerbates demyelination in mouse experimental autoimmune encephalomyelitis

BACKGROUND: Neuromyelitis optica (NMO) is a devastating inflammatory disorder of the optic nerves and spinal cord characterized by frequently recurring exacerbations of humoral inflammation. NMO is associated with the highly specific NMO-IgG biomarker, an antibody that binds the aquaporin-4 water ch...

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Bibliografiska uppgifter
Huvudupphovsmän: Saini, Harleen, Rifkin, Robert, Gorelik, Michael, Huang, Hwa, Ferguson, Zachary, Jones, Melina V, Levy, Michael
Materialtyp: Artigo
Språk:Inglês
Publicerad: BioMed Central 2013
Ämnen:
Research Article
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC3750922/
https://ncbi.nlm.nih.gov/pubmed/23927715
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2377-13-104
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