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Substrate Specificities and Conformational Flexibility of 3-Ketosteroid 9α-Hydroxylases
KshA is the oxygenase component of 3-ketosteroid 9α-hydroxylase, a Rieske oxygenase involved in the bacterial degradation of steroids. Consistent with its role in bile acid catabolism, KshA1 from Rhodococcus rhodochrous DSM43269 had the highest apparent specificity (k(cat)/K(m)) for steroids with an...
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| Main Authors: | , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American Society for Biochemistry and Molecular Biology
2014
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4162158/ https://ncbi.nlm.nih.gov/pubmed/25049233 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M114.575886 |
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