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Characterization of 3-Ketosteroid 9α-Hydroxylase, a Rieske Oxygenase in the Cholesterol Degradation Pathway of Mycobacterium tuberculosis

KshAB (3-Ketosteroid 9α-hydroxylase) is a two-component Rieske oxygenase (RO) in the cholesterol catabolic pathway of Mycobacterium tuberculosis. Although the enzyme has been implicated in pathogenesis, it has largely been characterized by bioinformatics and molecular genetics. Purified KshB, the re...

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Autori principali: Capyk, Jenna K., D'Angelo, Igor, Strynadka, Natalie C., Eltis, Lindsay D.
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society for Biochemistry and Molecular Biology 2009
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2665117/
https://ncbi.nlm.nih.gov/pubmed/19234303
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M900719200
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