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Characterization of 3-Ketosteroid 9α-Hydroxylase, a Rieske Oxygenase in the Cholesterol Degradation Pathway of Mycobacterium tuberculosis

KshAB (3-Ketosteroid 9α-hydroxylase) is a two-component Rieske oxygenase (RO) in the cholesterol catabolic pathway of Mycobacterium tuberculosis. Although the enzyme has been implicated in pathogenesis, it has largely been characterized by bioinformatics and molecular genetics. Purified KshB, the re...

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Detalhes bibliográficos
Main Authors: Capyk, Jenna K., D'Angelo, Igor, Strynadka, Natalie C., Eltis, Lindsay D.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2665117/
https://ncbi.nlm.nih.gov/pubmed/19234303
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M900719200
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