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Characterization of 3-Ketosteroid 9α-Hydroxylase, a Rieske Oxygenase in the Cholesterol Degradation Pathway of Mycobacterium tuberculosis

KshAB (3-Ketosteroid 9α-hydroxylase) is a two-component Rieske oxygenase (RO) in the cholesterol catabolic pathway of Mycobacterium tuberculosis. Although the enzyme has been implicated in pathogenesis, it has largely been characterized by bioinformatics and molecular genetics. Purified KshB, the re...

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Bibliografiske detaljer
Main Authors: Capyk, Jenna K., D'Angelo, Igor, Strynadka, Natalie C., Eltis, Lindsay D.
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Biochemistry and Molecular Biology 2009
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2665117/
https://ncbi.nlm.nih.gov/pubmed/19234303
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M900719200
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