Substrate Specificities and Conformational Flexibility of 3-Ketosteroid 9α-Hydroxylases

KshA is the oxygenase component of 3-ketosteroid 9α-hydroxylase, a Rieske oxygenase involved in the bacterial degradation of steroids. Consistent with its role in bile acid catabolism, KshA1 from Rhodococcus rhodochrous DSM43269 had the highest apparent specificity (k(cat)/K(m)) for steroids with an...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: Penfield, Jonathan S., Worrall, Liam J., Strynadka, Natalie C., Eltis, Lindsay D.
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: American Society for Biochemistry and Molecular Biology 2014
Gaiak:
Microbiology
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC4162158/
https://ncbi.nlm.nih.gov/pubmed/25049233
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M114.575886
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