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Intracellular Carbonic Anhydrase Activity Sensitizes Cancer Cell pH Signaling to Dynamic Changes in CO(2) Partial Pressure
Carbonic anhydrase (CA) enzymes catalyze the chemical equilibration among CO(2), HCO(3)(−) and H(+). Intracellular CA (CA(i)) isoforms are present in certain types of cancer, and growing evidence suggests that low levels correlate with disease severity. However, their physiological role remains uncl...
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| Hoofdauteurs: | , , , , |
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| Formaat: | Artigo |
| Taal: | Inglês |
| Gepubliceerd in: |
American Society for Biochemistry and Molecular Biology
2014
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| Onderwerpen: | |
| Online toegang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4162147/ https://ncbi.nlm.nih.gov/pubmed/25059669 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M114.547844 |
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