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The chemistry, physiology and pathology of pH in cancer

Cell survival is conditional on the maintenance of a favourable acid–base balance (pH). Owing to intensive respiratory CO(2) and lactic acid production, cancer cells are exposed continuously to large acid–base fluxes, which would disturb pH if uncorrected. The large cellular reservoir of H(+)-bindin...

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Detalhes bibliográficos
Main Authors: Swietach, Pawel, Vaughan-Jones, Richard D., Harris, Adrian L., Hulikova, Alzbeta
Formato: Artigo
Idioma:Inglês
Publicado em: The Royal Society 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3917353/
https://ncbi.nlm.nih.gov/pubmed/24493747
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1098/rstb.2013.0099
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