Crystal Structure of the cGMP-dependent Protein Kinase II Leucine Zipper and Rab11b Protein Complex Reveals Molecular Details of G-kinase-specific Interactions

cGMP-dependent protein kinase (PKG)-interacting proteins (GKIPs) mediate cellular targeting of PKG isoforms by interacting with their leucine zipper (LZ) domains. These interactions prevent aberrant signaling cross-talk between different PKG isotypes. To gain detailed insight into isotype-specific G...

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Detalhes bibliográficos
Main Authors: Reger, Albert S., Yang, Matthew P., Koide-Yoshida, Shizuyo, Guo, Elaine, Mehta, Shrenik, Yuasa, Keizo, Liu, Alan, Casteel, Darren E., Kim, Choel
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2014
Assuntos:
Protein Structure and Folding
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4162144/
https://ncbi.nlm.nih.gov/pubmed/25070890
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M114.575894
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