Llwytho...

Cooperative Hybridization of γPNA Miniprobes to a Repeating Sequence Motif and Application to Telomere Analysis

GammaPNA oligomers having one or two repeats of the sequence AATCCC were designed to hybridize to DNA having one or more repeats of the complementary TTAGGG sequence found in the human telomere. UV melting curves and surface plasmon resonance experiments demonstrate high affinity and cooperativity f...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Pham, Ha H., Murphy, Connor T., Sureshkumar, Gopalsamy, Ly, Danith H., Opresko, Patricia L., Armitage, Bruce A.
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: 2014
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC4162129/
https://ncbi.nlm.nih.gov/pubmed/25115693
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1039/c4ob00953c
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