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Autologous apoptotic cells preceding transplantation enhance survival in lethal murine graft-versus-host models
Acute graft-versus-host disease (GVHD) is induced by alloreactivity of donor T cells toward host antigens presented on antigen-presenting cells (APCs). Apoptotic cells are capable of inducing tolerance by altering APC maturation. Apoptosis can be induced by extracorporeal photopheresis (ECP). We dem...
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| Autors principals: | , , , , , , , |
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| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
American Society of Hematology
2014
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4162113/ https://ncbi.nlm.nih.gov/pubmed/25030062 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2014-02-555128 |
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