Autologous apoptotic cells preceding transplantation enhance survival in lethal murine graft-versus-host models

Acute graft-versus-host disease (GVHD) is induced by alloreactivity of donor T cells toward host antigens presented on antigen-presenting cells (APCs). Apoptotic cells are capable of inducing tolerance by altering APC maturation. Apoptosis can be induced by extracorporeal photopheresis (ECP). We dem...

Full description

Saved in:
Bibliographic Details
Main Authors: Florek, Mareike, Sega, Emanuela I., Leveson-Gower, Dennis B., Baker, Jeanette, Müller, Antonia M. S., Schneidawind, Dominik, Meyer, Everett, Negrin, Robert S.
Format: Artigo
Language:Inglês
Published: American Society of Hematology 2014
Subjects:
Transplantation
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4162113/
https://ncbi.nlm.nih.gov/pubmed/25030062
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2014-02-555128
Tags: Add Tag
No Tags, Be the first to tag this record!

Similar Items