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Diversity of the CD8(+) T cell repertoire elicited against an immunodominant epitope does not depend on the context of infection()

The diversity of the pathogen-specific T cell repertoire is believed to be important in allowing recognition of different pathogen epitopes and their variants and thereby reducing the opportunities for mutation-driven pathogen escape. However, the extent to which the TCR repertoire can be manipulate...

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Autores principales: Rudd, Brian D., Venturi, Vanessa, Smithey, Megan J., Way, Sing Sing, Davenport, Miles P., Nikolich-Zugich, Janko
Formato: Artigo
Lenguaje:Inglês
Publicado: 2010
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC4161216/
https://ncbi.nlm.nih.gov/pubmed/20164421
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.0903493
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