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Age-related dysregulation of CD8(+) T-cell memory specific for a persistent virus is independent of viral replication

The immune system devotes substantial resources to the life-long control of persistent pathogens, which were hypothesized to play an important role in immune aging. Specifically, the presence of latent herpesviruses has been correlated with immune exhaustion and shorter lifespan in octogenarian huma...

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Detalhes bibliográficos
Main Authors: Lang, Anna, Brien, James D., Messaoudi, Ilhem, Nikolich-Zugich, Janko
Formato: Artigo
Idioma:Inglês
Publicado em: 2008
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4161215/
https://ncbi.nlm.nih.gov/pubmed/18354208
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