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Age-related dysregulation of CD8(+) T-cell memory specific for a persistent virus is independent of viral replication
The immune system devotes substantial resources to the life-long control of persistent pathogens, which were hypothesized to play an important role in immune aging. Specifically, the presence of latent herpesviruses has been correlated with immune exhaustion and shorter lifespan in octogenarian huma...
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| Main Authors: | , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2008
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4161215/ https://ncbi.nlm.nih.gov/pubmed/18354208 |
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