2-Phenylindole and Arylsulphonamide: Novel Scaffolds Bactericidal against Mycobacterium tuberculosis

[Image: see text] A cellular activity-based screen on Mycobacterium tuberculosis (Mtb) H37Rv using a focused library from the AstraZeneca corporate collection led to the identification of 2-phenylindoles and arylsulphonamides, novel antimycobacterial scaffolds. Both the series were bactericidal in v...

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Autors principals: Naik, Maruti, Ghorpade, Sandeep, Jena, Lalit Kumar, Gorai, Gopinath, Narayan, Ashwini, Guptha, Supreeth, Sharma, Sreevalli, Dinesh, Neela, Kaur, Parvinder, Nandishaiah, Radha, Bhat, Jyothi, Balakrishnan, Gayathri, Humnabadkar, Vaishali, Ramachandran, Vasanthi, Naviri, Lava Kumar, Khadtare, Pallavi, Panda, Manoranjan, Iyer, Pravin S., Chatterji, Monalisa
Format: Artigo
Idioma:Inglês
Publicat: American Chemical Society 2014
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4160756/
https://ncbi.nlm.nih.gov/pubmed/25221657
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ml5001933
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