2-Phenylindole and Arylsulphonamide: Novel Scaffolds Bactericidal against Mycobacterium tuberculosis

[Image: see text] A cellular activity-based screen on Mycobacterium tuberculosis (Mtb) H37Rv using a focused library from the AstraZeneca corporate collection led to the identification of 2-phenylindoles and arylsulphonamides, novel antimycobacterial scaffolds. Both the series were bactericidal in v...

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Detalhes bibliográficos
Main Authors: Naik, Maruti, Ghorpade, Sandeep, Jena, Lalit Kumar, Gorai, Gopinath, Narayan, Ashwini, Guptha, Supreeth, Sharma, Sreevalli, Dinesh, Neela, Kaur, Parvinder, Nandishaiah, Radha, Bhat, Jyothi, Balakrishnan, Gayathri, Humnabadkar, Vaishali, Ramachandran, Vasanthi, Naviri, Lava Kumar, Khadtare, Pallavi, Panda, Manoranjan, Iyer, Pravin S., Chatterji, Monalisa
Formato: Artigo
Idioma:Inglês
Publicado em: American Chemical Society 2014
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4160756/
https://ncbi.nlm.nih.gov/pubmed/25221657
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ml5001933
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