Novel Cyclic Biphalin Analogue with Improved Antinociceptive Properties

[Image: see text] Two novel opioid analogues have been designed by substituting the native d-Ala residues in position 2,2′ of biphalin with two residues of d-penicillamine or l-penicillamine and by forming a disulfide bond between the thiol groups. The so-obtained compound 9 containing d-penicillami...

Celý popis

Uloženo v:
Podrobná bibliografie
Hlavní autoři: Mollica, Adriano, Carotenuto, Alfonso, Novellino, Ettore, Limatola, Antonio, Costante, Roberto, Pinnen, Francesco, Stefanucci, Azzurra, Pieretti, Stefano, Borsodi, Anna, Samavati, Reza, Zador, Ferenc, Benyhe, Sándor, Davis, Peg, Porreca, Frank, Hruby, Victor J.
Médium: Artigo
Jazyk:Inglês
Vydáno: American Chemical Society 2014
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4160744/
https://ncbi.nlm.nih.gov/pubmed/25221662
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ml500241n
Tagy: Přidat tag
Žádné tagy, Buďte první, kdo otaguje tento záznam!

Podobné jednotky