The benzene metabolite p-benzoquinone forms adducts with DNA bases that are excised by a repair activity from human cells that differs from an ethenoadenine glycosylase.

Benzene is a ubitiquous human environment mental carcinogen. One of the major metabolites is hydroquinone, which is oxidized in vivo to give p-benzoquinone (p-BQ). Both metabolites are toxic to human cells. p-BQ reacts with DNA to form benzetheno adducts with deoxycytidine, deoxyadenosine, and deoxy...

Täydet tiedot

Tallennettuna:
Bibliografiset tiedot
Päätekijät: Chenna, A, Hang, B, Rydberg, B, Kim, E, Pongracz, K, Bodell, W J, Singer, B
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: 1995
Aiheet:
Research Article
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC41607/
https://ncbi.nlm.nih.gov/pubmed/7597048
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