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All four known cyclic adducts formed in DNA by the vinyl chloride metabolite chloroacetaldehyde are released by a human DNA glycosylase.

We have previously reported that human cells and tissues contain a 1,N6-ethenoadenine (epsilon A) binding protein, which, through glycosylase activity, releases both 3-methyladenine (m3A) and epsilon A from DNA treated with methylating agents or the vinyl chloride metabolite chloroacetaldehyde, resp...

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Bibliografiske detaljer
Main Authors: Dosanjh, M K, Chenna, A, Kim, E, Fraenkel-Conrat, H, Samson, L, Singer, B
Format: Artigo
Sprog:Inglês
Udgivet: 1994
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC521446/
https://ncbi.nlm.nih.gov/pubmed/8302827
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