All four known cyclic adducts formed in DNA by the vinyl chloride metabolite chloroacetaldehyde are released by a human DNA glycosylase.

Lignende værker

• An unusual mechanism for the major human apurinic/apyrimidinic (AP) endonuclease involving 5′ cleavage of DNA containing a benzene-derived exocyclic adduct in the absence of an AP site
  af: Hang, B., et al.
  Udgivet: (1996)
• The benzene metabolite p-benzoquinone forms adducts with DNA bases that are excised by a repair activity from human cells that differs from an ethenoadenine glycosylase.
  af: Chenna, A, et al.
  Udgivet: (1995)
• Nucleoside adducts are formed by cooperative reaction of acetaldehyde and alcohols: possible mechanism for the role of ethanol in carcinogenesis.
  af: Fraenkel-Conrat, H, et al.
  Udgivet: (1988)
• A 55-kDa protein isolated from human cells shows DNA glycosylase activity toward 3,N(4)-ethenocytosine and the G/T mismatch
  af: Hang, B., et al.
  Udgivet: (1998)
• The vinyl chloride DNA derivative N2,3-ethenoguanine produces G----A transitions in Escherichia coli.
  af: Cheng, K C, et al.
  Udgivet: (1991)