The vinyl chloride DNA derivative N2,3-ethenoguanine produces G----A transitions in Escherichia coli.

Vinyl chloride is a known human and rodent carcinogen that forms several cyclic base derivatives in DNA. The mutagenic potential of these derivatives has been examined in vitro but not in vivo. One of these derivatives, N2,3-ethenoguanine (epsilon G), is known to base pair with both cytosine and thy...

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Detalhes bibliográficos

Publicado no:	Proc Natl Acad Sci U S A
Principais autores:	Cheng, K C, Preston, B D, Cahill, D S, Dosanjh, M K, Singer, B, Loeb, L A
Formato:	Artigo
Idioma:	Inglês
Publicado em:	National Academy of Sciences 1991
Assuntos:	Research Article
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC52849/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/1946466/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.88.22.9974
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