Lipid-like Nanomaterials for simultaneous gene expression and silencing in vivo

[Image: see text] New lipid-like nanomaterials were developed to simultaneously regulate expression of multiple genes. Self-assembled nanoparticles are capable of efficiently encapsulating pDNA and siRNA. These nanoparticles were shown to induce simultaneous gene expression and silencing both in vit...

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Main Authors: Dong, Yizhou, Eltoukhy, Ahmed A., Alabi, Christopher A., Khan, Omar F., Veiseh, Omid, Dorkin, J. Robert, Sirirungruang, Sasilada, Yin, Hao, Tang, Benjamin C., Pelet, Jeisa M., Chen, Delai, Gu, Zhen, Xue, Yuan, Langer, Robert, Anderson, Daniel G.
Format: Artigo
Jezik:Inglês
Izdano: 2014
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Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC4160381/
https://ncbi.nlm.nih.gov/pubmed/24623658
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/adhm.201400054
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