Lipid-like Nanomaterials for simultaneous gene expression and silencing in vivo

[Image: see text] New lipid-like nanomaterials were developed to simultaneously regulate expression of multiple genes. Self-assembled nanoparticles are capable of efficiently encapsulating pDNA and siRNA. These nanoparticles were shown to induce simultaneous gene expression and silencing both in vit...

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Autors principals: Dong, Yizhou, Eltoukhy, Ahmed A., Alabi, Christopher A., Khan, Omar F., Veiseh, Omid, Dorkin, J. Robert, Sirirungruang, Sasilada, Yin, Hao, Tang, Benjamin C., Pelet, Jeisa M., Chen, Delai, Gu, Zhen, Xue, Yuan, Langer, Robert, Anderson, Daniel G.
Format: Artigo
Idioma:Inglês
Publicat: 2014
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Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4160381/
https://ncbi.nlm.nih.gov/pubmed/24623658
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/adhm.201400054
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