Lipid-like Nanomaterials for simultaneous gene expression and silencing in vivo

[Image: see text] New lipid-like nanomaterials were developed to simultaneously regulate expression of multiple genes. Self-assembled nanoparticles are capable of efficiently encapsulating pDNA and siRNA. These nanoparticles were shown to induce simultaneous gene expression and silencing both in vit...

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Detalhes bibliográficos
Main Authors: Dong, Yizhou, Eltoukhy, Ahmed A., Alabi, Christopher A., Khan, Omar F., Veiseh, Omid, Dorkin, J. Robert, Sirirungruang, Sasilada, Yin, Hao, Tang, Benjamin C., Pelet, Jeisa M., Chen, Delai, Gu, Zhen, Xue, Yuan, Langer, Robert, Anderson, Daniel G.
Formato: Artigo
Idioma:Inglês
Publicado em: 2014
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4160381/
https://ncbi.nlm.nih.gov/pubmed/24623658
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/adhm.201400054
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