Lipid-like Nanomaterials for simultaneous gene expression and silencing in vivo

[Image: see text] New lipid-like nanomaterials were developed to simultaneously regulate expression of multiple genes. Self-assembled nanoparticles are capable of efficiently encapsulating pDNA and siRNA. These nanoparticles were shown to induce simultaneous gene expression and silencing both in vit...

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Détails bibliographiques
Auteurs principaux: Dong, Yizhou, Eltoukhy, Ahmed A., Alabi, Christopher A., Khan, Omar F., Veiseh, Omid, Dorkin, J. Robert, Sirirungruang, Sasilada, Yin, Hao, Tang, Benjamin C., Pelet, Jeisa M., Chen, Delai, Gu, Zhen, Xue, Yuan, Langer, Robert, Anderson, Daniel G.
Format: Artigo
Langue:Inglês
Publié: 2014
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Article
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4160381/
https://ncbi.nlm.nih.gov/pubmed/24623658
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/adhm.201400054
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