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Single-Walled Carbon Nanotubes Alleviate Autophagic/Lysosomal Defects in Primary Glia from a Mouse Model of Alzheimer’s Disease

[Image: see text] Defective autophagy in Alzheimer’s disease (AD) promotes disease progression in diverse ways. Here, we demonstrate impaired autophagy flux in primary glial cells derived from CRND8 mice that overexpress mutant amyloid precursor protein (APP). Functionalized single-walled carbon nan...

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書誌詳細
主要な著者: Xue, Xue, Wang, Li-Rong, Sato, Yutaka, Jiang, Ying, Berg, Martin, Yang, Dun-Sheng, Nixon, Ralph A., Liang, Xing-Jie
フォーマット: Artigo
言語:Inglês
出版事項: American Chemical Society 2014
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC4160261/
https://ncbi.nlm.nih.gov/pubmed/25115676
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/nl501839q
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