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Autophagy Failure in Alzheimer's Disease – Locating the Primary Defect
Autophagy, the major degradative pathway for organelles and long-lived proteins, is essential for the survival of neurons. Mounting evidence has implicated defective autophagy in the pathogenesis of several major neurodegenerative diseases, particularly Alzheimer's disease (AD). A continuum of...
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| Autores principales: | , |
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| Formato: | Artigo |
| Lenguaje: | Inglês |
| Publicado: |
2011
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| Acceso en línea: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3096679/ https://ncbi.nlm.nih.gov/pubmed/21296668 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.nbd.2011.01.021 |
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