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Autophagy Failure in Alzheimer's Disease – Locating the Primary Defect

Autophagy, the major degradative pathway for organelles and long-lived proteins, is essential for the survival of neurons. Mounting evidence has implicated defective autophagy in the pathogenesis of several major neurodegenerative diseases, particularly Alzheimer's disease (AD). A continuum of...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: Nixon, Ralph A., Yang, Dun-Sheng
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: 2011
Gaiak:
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC3096679/
https://ncbi.nlm.nih.gov/pubmed/21296668
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.nbd.2011.01.021
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