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Overexpression of TRB3 in muscle alters muscle fiber type and improves exercise capacity in mice
Increasing evidence suggests that TRB3, a mammalian homolog of Drosophila tribbles, plays an important role in cell growth, differentiation, and metabolism. In the liver, TRB3 binds and inhibits Akt activity, whereas in adipocytes, TRB3 upregulates fatty acid oxidation. In cultured muscle cells, TRB...
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| Main Authors: | , , , , , , , |
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| 格式: | Artigo |
| 語言: | Inglês |
| 出版: |
American Physiological Society
2014
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| 主題: | |
| 在線閱讀: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4159733/ https://ncbi.nlm.nih.gov/pubmed/24740654 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpregu.00027.2014 |
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