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PF-4708671 Activates AMPK Independently of p70S6K1 Inhibition
The P70 ribosomal protein S6 kinase 1 (P70S6K1) is activated by the mammalian target of rapamycin (mTORC1) and regulates proliferation, growth, and metabolism. PF-4708671 is a novel, cell-permeable, has been proposed to be a highly specific inhibitor of p70S6K1. It is used in micromolar concentratio...
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| 主要な著者: | , , , , , |
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| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
Public Library of Science
2014
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4159345/ https://ncbi.nlm.nih.gov/pubmed/25202971 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0107364 |
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