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Novel Proteome Extraction Method Illustrates a Conserved Immunological Signature of MSI-H Colorectal Tumors

Using a simple, environment friendly proteome extraction (TOP), we were able to optimize the analysis of clinical samples. Using our TOP method we analyzed a clinical cohort of microsatellite stable (MSS) and unstable (MSI-H) colorectal carcinoma (CRC). We identified a tumor cell specific, STAT1-cen...

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Detalhes bibliográficos
Publicado no:Mol Cell Proteomics
Main Authors: Vainer, Elez D., Kania-Almog, Juliane, Zatara, Ghadeer, Levin, Yishai, Vainer, Gilad W.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8015011/
https://ncbi.nlm.nih.gov/pubmed/32641473
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/mcp.RA120.002152
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