Structural characterization of anti-inflammatory Immunoglobulin G Fc proteins

Immunoglobulin G (IgG) is a central mediator of host defense due to its ability to recognize and eliminate pathogens. The recognition and effector responses are encoded on distinct regions of IgGs. The diversity of the antigen recognition Fab domains accounts for IgG's ability to bind with high...

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Autores principales: Ahmed, Alysia A., Giddens, John, Pincetic, Andrew, Lomino, Joseph V., Ravetch, Jeffrey V., Wang, Lai-Xi, Bjorkman, Pamela J.
Formato: Artigo
Lenguaje:Inglês
Publicado: 2014
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Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC4159253/
https://ncbi.nlm.nih.gov/pubmed/25036289
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jmb.2014.07.006
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