Investigating the Physiological Roles of Low-Efficiency d-Mannonate and d-Gluconate Dehydratases in the Enolase Superfamily: Pathways for the Catabolism of l-Gulonate and l-Idonate

[Image: see text] The sequence/function space in the d-mannonate dehydratase subgroup (ManD) of the enolase superfamily was investigated to determine how enzymatic function diverges as sequence identity decreases [Wichelecki, D. J., et al. (2014) Biochemistry53, 2722–2731]. That study revealed that...

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Bibliographic Details
Main Authors: Wichelecki, Daniel J., Vendiola, Jean Alyxa Ferolin, Jones, Amy M., Al-Obaidi, Nawar, Almo, Steven C., Gerlt, John A.
Format: Artigo
Language:Inglês
Published: American Chemical Society 2014
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4159206/
https://ncbi.nlm.nih.gov/pubmed/25145794
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/bi500837w
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