טוען...
A genome-wide RNAi screen identifies potential drug targets in a C. elegans model of α1-antitrypsin deficiency
α1-Antitrypsin deficiency (ATD) is a common genetic disorder that can lead to end-stage liver and lung disease. Although liver transplantation remains the only therapy currently available, manipulation of the proteostasis network (PN) by small molecule therapeutics offers great promise. To accelerat...
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| Main Authors: | , , , , , , , , , , |
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| פורמט: | Artigo |
| שפה: | Inglês |
| יצא לאור: |
Oxford University Press
2014
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| נושאים: | |
| גישה מקוונת: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4159156/ https://ncbi.nlm.nih.gov/pubmed/24838285 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/hmg/ddu236 |
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