The Nuclear-Retained Noncoding RNA MALAT1 Regulates Alternative Splicing by Modulating SR Splicing Factor Phosphorylation

Alternative splicing (AS) of pre-mRNA is utilized by higher eukaryotes to achieve increased transcriptome and proteomic complexity. The serine/arginine (SR) splicing factors regulate tissue- or cell-type-specific AS in a concentration- and phosphorylation-dependent manner. However, the mechanisms th...

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Главные авторы: Tripathi, Vidisha, Ellis, Jonathan D., Shen, Zhen, Song, David Y., Pan, Qun, Watt, Andrew T., Freier, Susan M., Bennett, C. Frank, Sharma, Alok, Bubulya, Paula A., Blencowe, Benjamin J., Prasanth, Supriya G., Prasanth, Kannanganattu V.
Формат: Artigo
Язык:Inglês
Опубликовано: 2010
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Article
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC4158944/
https://ncbi.nlm.nih.gov/pubmed/20797886
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molcel.2010.08.011
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