The Nuclear-Retained Noncoding RNA MALAT1 Regulates Alternative Splicing by Modulating SR Splicing Factor Phosphorylation

Alternative splicing (AS) of pre-mRNA is utilized by higher eukaryotes to achieve increased transcriptome and proteomic complexity. The serine/arginine (SR) splicing factors regulate tissue- or cell-type-specific AS in a concentration- and phosphorylation-dependent manner. However, the mechanisms th...

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Autors principals: Tripathi, Vidisha, Ellis, Jonathan D., Shen, Zhen, Song, David Y., Pan, Qun, Watt, Andrew T., Freier, Susan M., Bennett, C. Frank, Sharma, Alok, Bubulya, Paula A., Blencowe, Benjamin J., Prasanth, Supriya G., Prasanth, Kannanganattu V.
Format: Artigo
Idioma:Inglês
Publicat: 2010
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Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4158944/
https://ncbi.nlm.nih.gov/pubmed/20797886
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molcel.2010.08.011
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